pregabalin capsules 300 mg nerve pain relief tablets, commonly known under the brand name Lyrica, provide a medication primarily used for the treatment of neuropathic pain, fibromyalgia, and generalized anxiety disorder. Each capsule contains 300mg of pregabalin, a chemical compound with the formula C8H17N O2, which modulates the release of certain neurotransmitters, reducing the sensation of pain and anxiety.
Mode of Action
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) – an inhibitory neurotransmitter. It is also suggested that presynaptic binding of pregabalin to voltage-gated calcium channels is key to the antiseizure and antinociceptive. By binding presynaptically to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system, pregabalin modulates the release of several excitatory neurotransmitters including glutamate, substance-P, norepinephrine, and calcitonin gene related peptide. In addition, pregabalin prevents the alpha2-delta subunit from being trafficked from the dorsal root ganglia to the spinal dorsal horn, which may also contribute to the mechanism of action.
Uses of Pregabaline Nerve Pain Relief Tablets
- It provides effective relief from neuropathic pain, fibromyalgia, and generalized anxiety disorder.
- It is fast-acting with a quick onset of relief, often within a few hours.
- With favourable side effect profile, most patients well-tolerate it when used in the prescribed dose.
- It is particularly useful for patients who experience chronic pain conditions or anxiety that disrupts their quality of life.
- It is also used as adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older.
Side Effects of Overdose
The overdose of pregabalin can lead to dizziness, drowsiness, confusion, sometimes allergic reactions and respiratory depression. In severe cases, it may result in loss of consciousness or coma. Immediate clinical assistance is crucial if you suspect overdose signs and symptoms.
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